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Gene Expression Literature Summary
Assay
Age
In situ RNA (section)
10.5 DPC

6 matching records from 6 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Lhx8  LIM homeobox protein 8   (Synonyms: L3, Lhx7)
Results  Reference
1J:225434 Cesario JM, Landin Malt A, Deacon LJ, Sandberg M, Vogt D, Tang Z, Zhao Y, Brown S, Rubenstein JL, Jeong J, Lhx6 and Lhx8 promote palate development through negative regulation of a cell cycle inhibitor gene, p57Kip2. Hum Mol Genet. 2015 Sep 1;24(17):5024-39
1*J:48134 Grigoriou M, Tucker AS, Sharpe PT, Pachnis V, Expression and regulation of Lhx6 and Lhx7, a novel subfamily of LIM homeodomain encoding genes, suggests a role in mammalian head development. Development. 1998 Jun;125(11):2063-74
1*J:316526 Landin Malt A, Cesario JM, Tang Z, Brown S, Jeong J, Identification of a face enhancer reveals direct regulation of LIM homeobox 8 (Lhx8) by wingless-int (WNT)/beta-catenin signaling. J Biol Chem. 2014 Oct 31;289(44):30289-30301
1J:225813 Puelles L, Morales-Delgado N, Merchan P, Castro-Robles B, Martinez-de-la-Torre M, Diaz C, Ferran JL, Radial and tangential migration of telencephalic somatostatin neurons originated from the mouse diagonal area. Brain Struct Funct. 2016 Jul;221(6):3027-65
1*J:49930 Tucker AS, Yamada G, Grigoriou M, Pachnis V, Sharpe PT, Fgf-8 determines rostral-caudal polarity in the first branchial arch. Development. 1999 Jan;126(1):51-61
1J:309090 Xu J, Liu H, Lan Y, Adam M, Clouthier DE, Potter S, Jiang R, Hedgehog signaling patterns the oral-aboral axis of the mandibular arch. Elife. 2019 Jan 14;8:e40315

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory